A high throughput, interactive imaging, bright-field wound healing assay
نویسندگان
چکیده
منابع مشابه
A high throughput, interactive imaging, bright-field wound healing assay.
The wound healing assay is a commonly used technique to measure cell motility and migration. Traditional methods of performing the wound healing assay suffer from low throughput and a lack of quantitative data analysis. We have developed a new method to perform a high-throughput wound healing assay that produces quantitative data using the LEAP™ instrument. The LEAP™ instrument is used to creat...
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BACKGROUND Cell migration is a complex phenomenon that requires the coordination of numerous cellular processes. Investigation of cell migration and its underlying biology is of interest to basic scientists and those in search of therapeutics. Current migration assays for screening small molecules, siRNAs, or other perturbations are difficult to perform in parallel at the scale required to scre...
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Endothelial migration is an important process in the formation of blood vessels and the repair of damaged tissue. To study this process in the laboratory, versatile and reliable migration assays are essential. The purpose of this study was to investigate whether the microfluidic version of the conventional wound-healing assay is a useful research tool for vascular science. Endothelial cells wer...
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ژورنال
عنوان ژورنال: Cytometry Part A
سال: 2011
ISSN: 1552-4922
DOI: 10.1002/cyto.a.21029